GIHCG

Across TCGA pan-cancer cohorts, GIHCG RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated GIHCG data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher GIHCG RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GIHCG expression acts as an unfavorable survival marker, although some lineages such as PAAD and DLBC show a favorable association.

KIRC, LIHC, and KICH are the cancer types where GIHCG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.725	0.864	<.001	163	view →
LIHC	OS	Median	All	0.424	0.593	<.001	77	view →
KICH	DFS	Median	III,IV	0.240	1.000	.001	63	view →
ACC	DFS	Median	All	0.281	0.632	<.001	58	view →
PAAD	DFS	Quartile	All	0.486	0.214	.001	40	view →
STAD	OS	Median	II,III,IV	0.324	0.529	.010	38	view →
DLBC	DFS	Tertile	All	0.984	0.404	.018	34	view →
UCS	DFS	Median	II,III,IV	0.614	0.259	.002	32	view →
ESCA	OS	Median	All	1.000	0.659	.020	24	view →
LUAD	OS	Tertile	All	0.494	0.172	.001	19	view →
BRCA	OS	Quartile	II,III,IV	0.924	0.861	.034	15	view →
THYM	OS	Tertile	All	1.000	0.688	.005	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

GIHCG–KIRC (DFS)

Open the KIRC breakdown →