Across TCGA patient cohorts, GIGYF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,842 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GIGYF2-associated proteins across cancer lineages are UBA3, HNRNPLL, and XRCC5. Each is linked with GIGYF2 in more than 5 cancer types. Because this analysis shows association rather than direction, both GIGYF2-to-partner and partner-to-GIGYF2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GIGYF2→partner) and Y-score (partner→GIGYF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	UBA3 →	+0.212	+0.231	<.001	.001	3	5
GBM	HNRNPLL →	+0.308	+0.429	<.001	<.001	3	5
HNSC	XRCC5 →	+0.246	+0.440	<.001	<.001	3	5
GBM	XRCC6 →	+0.239	+0.312	.001	.001	3	5
GBM	ILKAP →	+0.381	+0.337	<.001	.001	3	5
OV	DIS3L2 →	+0.334	+0.694	.001	<.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,842 associations by consensus.

Exploration

GIGYF2 survival (RNA) · tumor vs normal (RNA) · all GIGYF2 data types