Across TCGA patient cohorts, GIGYF2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,782 significant associations in total. COAD shows the largest number of these associations.

The most reproducible GIGYF2-associated genes across cancer lineages are MRPL44, NCL, and UBE2F. Each is linked with GIGYF2 in more than 5 cancer types. Because this analysis shows association rather than direction, both GIGYF2-to-partner and partner-to-GIGYF2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIGYF2→partner) and Y-score (partner→GIGYF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRPL44 →	+0.668	+0.179	.001	<.001	3	6
UCEC	NCL →	+0.645	+0.127	<.001	.001	3	6
HNSC	UBE2F →	+0.499	+0.164	.001	.002	3	5
UCEC	HJURP →	+1.089	+0.171	<.001	<.001	3	5
COAD	LMOD1 →	-1.738	-0.188	<.001	<.001	3	5
OV	DTYMK →	+0.812	+0.213	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,782 associations by consensus.

Exploration

GIGYF2 survival (RNA) · tumor vs normal (RNA) · all GIGYF2 data types