Across TCGA cell cohorts, GIGYF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,117 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GIGYF2-associated GO terms across cancer lineages are Negative regulation of translational initiation, Pre-mRNA catabolic process, and RISC complex assembly. Each is linked with GIGYF2 in more than 16 cancer types. Because this analysis shows association rather than direction, both GIGYF2-to-partner and partner-to-GIGYF2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GIGYF2→partner) and Y-score (partner→GIGYF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of translational initiation →	+0.111	+0.650	<.001	<.001	3	17
BONE	Pre-mRNA catabolic process →	+0.240	+0.779	<.001	<.001	3	16
LUNG_SCLC	RISC complex assembly →	+0.143	+0.732	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.074	+1.074	<.001	<.001	3	16
SKIN	Endosomal transport →	+0.069	+0.976	<.001	<.001	3	15
SOFT_TISSUE	Positive regulation of TORC2 signaling →	+0.104	+1.228	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,117 associations by consensus.

Exploration

GIGYF2 survival (RNA) · tumor vs normal (RNA) · all GIGYF2 data types