GID8

Across TCGA patient cohorts, GID8 protein abundance is significantly associated with the RNA expression of many other genes, with 15,502 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GID8-associated genes across cancer lineages are NUF2, AURKA, and MAPK14. Each is linked with GID8 in more than 4 cancer types. Because this analysis shows association rather than direction, both GID8-to-partner and partner-to-GID8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GID8 versus NUF2 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GID8→partner) and Y-score (partner→GID8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NUF2 →	+1.174	+0.219	<.001	.001	3	5
LUAD	AURKA →	+0.877	+0.111	<.001	.003	3	5
HNSC	MAPK14 →	+0.454	+0.204	<.001	<.001	3	4
LSCC	STMN1 →	+0.869	+0.137	<.001	<.001	3	4
COAD	MRS2 →	+0.472	+0.177	<.001	.008	3	4
BRCA	CENPN →	+0.922	+0.270	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,502 associations by consensus.

GID8 vs NUF2 — BRCA

Explore this scatter interactively →