GID8

Across TCGA cell cohorts, GID8 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,561 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GID8-associated GO terms across cancer lineages are Regulation of DNA repair, Positive regulation of stem cell population maintenance, and Regulation of transcription initiation by RNA polymerase II. Each is linked with GID8 in more than 15 cancer types. Because this analysis shows association rather than direction, both GID8-to-partner and partner-to-GID8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by GID8-low versus GID8-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GID8→partner) and Y-score (partner→GID8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of DNA repair →	+0.068	+0.532	<.001	<.001	3	16
OVARY	Positive regulation of stem cell population maintenance →	+0.077	+0.681	<.001	<.001	3	15
SOFT_TISSUE	Regulation of transcription initiation by RNA polymerase II →	+0.074	+0.813	<.001	<.001	3	15
OESOPHAGUS	Promoter clearance during DNA-templated transcription →	+0.166	+0.877	.001	.007	3	15
OESOPHAGUS	RNA polymerase II promoter clearance →	+0.166	+0.877	.001	.007	3	15
OESOPHAGUS	Regulation of mRNA stability →	+0.070	+1.152	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,561 associations by consensus.

Regulation of DNA repair by GID8 expression — BONE

Explore this box plot interactively →