GHSR

Across TCGA cell cohorts, GHSR RNA expression is significantly associated with the go_rna of many other GO terms, with 566 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible GHSR-associated GO terms across cancer lineages are Fatty acid derivative metabolic process, Regulation of cell-substrate adhesion, and Pyramidal neuron development. Each is linked with GHSR in more than 3 cancer types. Because this analysis shows association rather than direction, both GHSR-to-partner and partner-to-GHSR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid derivative metabolic process grouped by GHSR-low versus GHSR-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GHSR→partner) and Y-score (partner→GHSR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Fatty acid derivative metabolic process →	-0.041	-0.019	.003	.006	3	4
UPPER_AERODIGESTIVE_TRACT	Regulation of cell-substrate adhesion →	+0.051	+0.042	.002	.007	3	4
LARGE_INTESTINE	Pyramidal neuron development →	+0.080	+0.014	.009	.002	3	4
SKIN	Positive regulation of intracellular protein transport →	+0.045	+0.017	.003	.001	3	4
CNS	Positive regulation of protein polymerization →	+0.057	+0.016	<.001	.007	3	4
OVARY	Insulin receptor signaling pathway →	+0.046	+0.026	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 566 associations by consensus.

Fatty acid derivative metabolic process by GHSR expression — SKIN

Explore this box plot interactively →