GHRLOS

Across TCGA patient cohorts, GHRLOS RNA expression is significantly associated with the mutation status of many other genes, with 10,988 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GHRLOS-associated genes across cancer lineages are TP53, TACC2, and PTEN. Each is linked with GHRLOS in more than 5 cancer types. Because this analysis shows association rather than direction, both GHRLOS-to-partner and partner-to-GHRLOS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by GHRLOS-low versus GHRLOS-high in LIHC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GHRLOS→partner) and Y-score (partner→GHRLOS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	TP53 →	+1.365	+0.292	<.001	<.001	3	6
UCEC	TACC2 →	+2.076	+0.476	<.001	<.001	3	4
LGG	PTEN →	+3.057	+0.314	<.001	<.001	3	3
BLCA	SSPOP →	+2.064	+0.436	<.001	.001	3	3
UCEC	NOP56 →	+4.119	+0.507	<.001	<.001	3	3
UCEC	TRPV4 →	+2.616	+0.473	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,988 associations by consensus.

TP53 by GHRLOS expression — LIHC

Explore this box plot interactively →