GHRHR

Across TCGA patient cohorts, GHRHR protein abundance is significantly associated with the RNA expression of many other genes, with 88 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GHRHR-associated genes across cancer lineages are ACR, SC5D, and CLDN16. Each is linked with GHRHR in more than 1 cancer types. Because this analysis shows association rather than direction, both GHRHR-to-partner and partner-to-GHRHR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GHRHR versus ACR in UCEC, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GHRHR→partner) and Y-score (partner→GHRHR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACR →	-0.502	-0.531	.007	<.001	3	1
UCEC	SC5D →	-0.901	-0.465	.002	.007	3	1
UCEC	CLDN16 →	-2.862	-0.589	.002	.008	3	1
UCEC	KMT2A →	-0.448	-0.634	.009	.003	3	1
UCEC	ATL2 →	-0.851	-0.600	.004	.002	3	1
UCEC	MAX →	-0.841	-0.471	.008	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

GHRHR vs ACR — UCEC

Explore this scatter interactively →