GHRHR

Across TCGA patient cohorts, GHRHR protein abundance is significantly associated with the protein abundance of many other proteins, with 486 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GHRHR-associated proteins across cancer lineages are SKI_S347, TAPBP, and TBX2. Each is linked with GHRHR in more than 1 cancer types. Because this analysis shows association rather than direction, both GHRHR-to-partner and partner-to-GHRHR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GHRHR versus SKI_S347 in UCEC, with a Pearson correlation of 0.97.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GHRHR→partner) and Y-score (partner→GHRHR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SKI_S347 →	+0.773	+0.608	<.001	<.001	3	1
UCEC	TAPBP →	-1.217	-0.517	<.001	.001	3	1
UCEC	TBX2 →	+0.739	+0.531	<.001	<.001	3	1
UCEC	TJP1_Y132 →	+0.719	+0.608	<.001	<.001	3	1
UCEC	TMEM181 →	-0.612	-0.485	.006	.003	3	1
UCEC	UPF3B_S327 →	-1.072	-0.785	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 486 associations by consensus.

GHRHR vs SKI_S347 — UCEC

Explore this scatter interactively →