GHRHR

Across TCGA cell cohorts, GHRHR RNA expression is significantly associated with the go_rna of many other GO terms, with 1,116 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GHRHR-associated GO terms across cancer lineages are Regulation of dendrite extension, Spermine transport, and Oligodendrocyte development. Each is linked with GHRHR in more than 2 cancer types. Because this analysis shows association rather than direction, both GHRHR-to-partner and partner-to-GHRHR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of dendrite extension grouped by GHRHR-low versus GHRHR-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GHRHR→partner) and Y-score (partner→GHRHR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of dendrite extension →	-0.152	-0.834	.001	<.001	3	3
OVARY	Spermine transport →	+0.104	+0.179	<.001	.009	3	3
CNS	Oligodendrocyte development →	+0.074	+0.132	.003	.006	3	3
BONE	Regulation of stem cell differentiation →	+0.076	+0.553	<.001	<.001	3	3
BONE	Positive regulation of circadian sleep/wake cycle, non-REM sleep →	+0.142	+0.573	<.001	<.001	3	3
BONE	Response to axon injury →	-0.125	-0.411	.002	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,116 associations by consensus.

Regulation of dendrite extension by GHRHR expression — BONE

Explore this box plot interactively →