GH2

Across TCGA patient cohorts, GH2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,534 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible GH2-associated GO terms across cancer lineages are tRNA 5'-end processing, RNA capping, and Mitotic DNA replication. Each is linked with GH2 in more than 9 cancer types. Because this analysis shows association rather than direction, both GH2-to-partner and partner-to-GH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA 5'-end processing grouped by GH2-low versus GH2-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GH2→partner) and Y-score (partner→GH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	tRNA 5'-end processing →	+0.037	+0.594	<.001	<.001	3	9
SARC	RNA capping →	+0.029	+0.022	.001	<.001	3	8
STAD	Mitotic DNA replication →	+0.058	+0.091	<.001	<.001	3	8
STAD	Regulation of aerobic respiration →	+0.067	+0.097	<.001	<.001	3	8
THCA	Aerobic respiration →	+0.025	+0.011	<.001	.009	1	10
TGCT	RNA 5'-end processing →	+0.045	+0.635	<.001	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,534 associations by consensus.

tRNA 5'-end processing by GH2 expression — TGCT

Explore this box plot interactively →