GH2

Across TCGA cell cohorts, GH2 RNA expression is significantly associated with the mutation status of many other genes, with 147 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GH2-associated genes across cancer lineages are HR, HDAC6, and RAPGEF1. Each is linked with GH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GH2-to-partner and partner-to-GH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HR grouped by GH2-low versus GH2-high in BREAST.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GH2→partner) and Y-score (partner→GH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	HR →	+5.781	+0.030	.001	<.001	3	2
STOMACH	HDAC6 →	+3.247	+0.054	.003	<.001	3	2
BLOOD_Leukemia	RAPGEF1 →	+4.384	+0.017	.006	<.001	3	2
BLOOD_Leukemia	ZNF569 →	+3.969	+0.014	.009	<.001	3	2
BLOOD_Leukemia	TLR9 →	+3.969	+0.014	.009	<.001	3	2
LUNG_NSCLC_LUAD	SMYD1 →	+3.696	+0.043	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 147 associations by consensus.

HR by GH2 expression — BREAST

Explore this box plot interactively →