GGTLC4P

Across TCGA pan-cancer cohorts, GGTLC4P RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated GGTLC4P data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher GGTLC4P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated GGTLC4P expression acts as an unfavorable survival marker, although some lineages such as KIRP and LUAD show a favorable association.

KIRP, LUSC, and ACC are the cancer types where GGTLC4P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	IV	0.623	0.039	.001	55	view →
LUSC	OS	Median	III,IV	0.180	0.836	<.001	49	view →
ACC	OS	Quartile	II,III,IV	0.574	0.934	.001	42	view →
LUAD	DFS	Quartile	All	0.828	0.693	.002	36	view →
BRCA	DFS	Quartile	II,III,IV	0.848	0.922	.005	31	view →
MESO	DFS	Median	II,III,IV	0.248	0.653	.003	24	view →
LGG	OS	Median	All	0.326	0.567	<.001	24	view →
CHOL	DFS	Median	All	0.695	0.200	.001	22	view →
GBM	DFS	Median	All	0.205	0.302	.006	20	view →
UCEC	OS	Median	All	0.830	0.905	.003	18	view →
THCA	OS	Median	III,IV	0.898	0.978	.009	17	view →
CESC	OS	Tertile	II,III,IV	0.732	0.405	.015	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

GGTLC4P–KIRP (DFS)

Open the KIRP breakdown →