Across TCGA patient cohorts, GGTA1 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GGTA1-associated genes across cancer lineages are RNA5SP414, MLECP1, and OR4K3. Each is linked with GGTA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GGTA1-to-partner and partner-to-GGTA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGTA1→partner) and Y-score (partner→GGTA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP414 →	+1.253	+4.840	<.001	.003	3	1
UCEC	MLECP1 →	+0.113	+5.226	.003	.003	3	1
UCEC	OR4K3 →	+0.087	+5.666	.003	<.001	3	1
UCEC	BPTFP1 →	+0.113	+4.621	.003	.008	3	1
UCEC	MIR3619 →	+1.056	+4.188	<.001	.009	3	1
UCEC	RNU6-1082P →	+0.416	+4.551	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

GGTA1 survival (RNA) · tumor vs normal (RNA) · all GGTA1 data types