GGT7

Across TCGA pan-cancer cohorts, GGT7 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated GGT7 data layer compared with 26 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher GGT7 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated GGT7 expression acts as an unfavorable survival marker.

THYM, OV, and PCPG are the cancer types where GGT7 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	All	0.604	0.967	<.001	39	view →
OV	OS	Median	III,IV	0.021	0.837	<.001	24	view →
PCPG	DFS	Median	All	0.229	0.822	.024	6	view →
LUSC	DFS	Median	II,III,IV	0.199	0.748	.006	6	view →
LIHC	OS	Median	All	0.255	0.773	.012	6	view →
LUAD	DFS	Median	All	0.098	0.768	<.001	6	view →
SKCM	OS	Median	All	0.420	0.783	.025	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

GGT7–THYM (OS)

Open the THYM breakdown →