GGT7

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, GGT7 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated GGT7 data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher GGT7 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GGT7 expression acts as an unfavorable survival marker.

HNSC, LUAD, and UCEC are the cancer types where GGT7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCDFSQuartileII,III,IV0.6190.894.00327view →
LUADDFSQuartileAll0.8550.996.0116view →
UCECDFSQuartileII,III,IV0.6131.000.0386view →
PDACDFSMedianAll0.6930.813.0175view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

GGT7–HNSC (DFS)

Kaplan–Meier survival curve for GGT7 mass-spec protein-high vs -low samples in HNSC.

Open the HNSC breakdown →

Exploration