GGT7

Across TCGA patient cohorts, GGT7 mutation is significantly associated with the RNA expression of many other genes, with 2,254 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GGT7-associated genes across cancer lineages are RNU6-520P, IGHD7-27, and RNA5SP420. Each is linked with GGT7 in more than 2 cancer types. Because this analysis shows association rather than direction, both GGT7-to-partner and partner-to-GGT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-520P grouped by GGT7-low versus GGT7-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGT7→partner) and Y-score (partner→GGT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-520P →	+0.354	+5.368	<.001	.005	3	3
CESC	IGHD7-27 →	+1.287	+5.569	<.001	.002	3	3
LUSC	RNA5SP420 →	+1.047	+5.309	<.001	.003	3	3
LUSC	RNA5SP408 →	+1.013	+6.918	<.001	<.001	3	3
SKCM	MT-RNR2 →	-0.915	-3.578	.007	.003	3	2
OV	SNORD115-5 →	+0.314	+6.333	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,254 associations by consensus.

RNU6-520P by GGT7 expression — HNSC

Explore this box plot interactively →