GGT1

Across TCGA patient cohorts, GGT1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,609 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GGT1-associated genes across cancer lineages are PATZ1, EMC9, and UBE2S. Each is linked with GGT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GGT1-to-partner and partner-to-GGT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GGT1 versus PATZ1 in LSCC, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGT1→partner) and Y-score (partner→GGT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PATZ1 →	+0.917	+0.914	.005	.006	3	2
LSCC	EMC9 →	+0.730	+1.125	.005	.006	3	2
BRCA	UBE2S →	+2.239	+1.533	.002	.004	2	3
LSCC	CLEC2B →	-1.741	-1.005	<.001	.001	3	2
LSCC	VAX2 →	+1.148	+1.151	.002	.007	3	2
LSCC	ONECUT2 →	+1.927	+1.447	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,609 associations by consensus.

GGT1 vs PATZ1 — LSCC

Explore this scatter interactively →