GGT1

Across TCGA cell cohorts, GGT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,464 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GGT1-associated GO terms across cancer lineages are Leukotriene D4 biosynthetic process, Peptide metabolic process, and Peptide biosynthetic process. Each is linked with GGT1 in more than 15 cancer types. Because this analysis shows association rather than direction, both GGT1-to-partner and partner-to-GGT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Leukotriene D4 biosynthetic process grouped by GGT1-low versus GGT1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GGT1→partner) and Y-score (partner→GGT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Leukotriene D4 biosynthetic process →	+1.543	+2.495	<.001	.001	3	16
LUNG_NSCLC_LUSC	Peptide metabolic process →	+0.127	+1.822	<.001	<.001	3	12
LIVER	Peptide biosynthetic process →	+0.275	+3.647	<.001	<.001	3	11
LARGE_INTESTINE	Regulation of viral entry into host cell →	+0.143	+1.713	<.001	.001	3	10
STOMACH	L-cysteine biosynthetic process →	+0.727	+1.955	.005	.007	2	11
LARGE_INTESTINE	Peptide modification →	+0.158	+2.481	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,464 associations by consensus.

Leukotriene D4 biosynthetic process by GGT1 expression — STOMACH

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