GGPS1

Across TCGA cell cohorts, GGPS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,638 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GGPS1-associated GO terms across cancer lineages are Geranyl diphosphate metabolic process, Establishment of protein localization to endoplasmic reticulum membrane, and Geranylgeranyl diphosphate biosynthetic process. Each is linked with GGPS1 in more than 18 cancer types. Because this analysis shows association rather than direction, both GGPS1-to-partner and partner-to-GGPS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Geranyl diphosphate metabolic process grouped by GGPS1-low versus GGPS1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GGPS1→partner) and Y-score (partner→GGPS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Geranyl diphosphate metabolic process →	+0.190	+0.788	<.001	<.001	3	19
SKIN	Establishment of protein localization to endoplasmic reticulum membrane →	+0.127	+0.980	<.001	<.001	3	14
BONE	Geranylgeranyl diphosphate biosynthetic process →	+0.201	+0.952	<.001	<.001	3	12
BLOOD_Myeloma	Negative regulation of transcription by RNA polymerase I →	+0.146	+1.163	<.001	.001	3	12
BONE	COPII vesicle coating →	+0.111	+1.149	<.001	<.001	3	12
SKIN	Positive regulation of eating behavior →	+1.260	+0.610	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,638 associations by consensus.

Geranyl diphosphate metabolic process by GGPS1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →