GGNBP2

Across TCGA pan-cancer cohorts, GGNBP2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated GGNBP2 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher GGNBP2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated GGNBP2 expression acts as an unfavorable survival marker, although some lineages such as PDAC and UCEC show a favorable association.

PDAC, UCEC, and LSCC are the cancer types where GGNBP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	II,III,IV	0.941	0.706	.004	23	view →
UCEC	OS	Quartile	III,IV	1.000	0.294	.037	12	view →
LSCC	OS	Median	III,IV	0.755	0.939	.032	4	view →
LUAD	DFS	Median	III,IV	0.972	0.547	.013	4	view →
HNSC	OS	Median	II,III,IV	0.809	0.629	.013	4	view →
CCRCC	DFS	Tertile	All	0.894	0.502	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

GGNBP2–PDAC (OS)

Open the PDAC breakdown →