GGNBP2

Across TCGA patient cohorts, GGNBP2 mutation is significantly associated with the RNA expression of many other genes, with 3,883 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GGNBP2-associated genes across cancer lineages are OR52N1, RNU2-48P, and MIR6854. Each is linked with GGNBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GGNBP2-to-partner and partner-to-GGNBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52N1 grouped by GGNBP2-low versus GGNBP2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGNBP2→partner) and Y-score (partner→GGNBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR52N1 →	+0.111	+2.878	.005	.008	3	2
STAD	RNU2-48P →	+0.419	+3.695	.002	.002	3	2
STAD	MIR6854 →	+0.402	+3.084	.003	.002	3	2
LIHC	ZSWIM5P1 →	+0.030	+5.676	.003	.001	3	2
UCEC	COX5A →	+0.306	+1.917	.005	.008	3	2
UCEC	AURKB →	+0.531	+3.016	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,883 associations by consensus.

OR52N1 by GGNBP2 expression — BLCA

Explore this box plot interactively →