GGNBP2

Across TCGA cell cohorts, GGNBP2 mutation is significantly associated with the drug of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GGNBP2-associated genes across cancer lineages are Leflunomide, 50869, and Ispinesib Mesylate. Each is linked with GGNBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GGNBP2-to-partner and partner-to-GGNBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Leflunomide grouped by GGNBP2-low versus GGNBP2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGNBP2→partner) and Y-score (partner→GGNBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Leflunomide →	+0.316	+2.678	.012	.037	3	1
LARGE_INTESTINE	50869 →	+0.440	+2.649	.037	.046	3	1
LARGE_INTESTINE	Ispinesib Mesylate →	+0.745	+2.652	.021	.045	3	1
LARGE_INTESTINE	CX-5461 →	+0.759	+2.652	.009	.045	3	1
LARGE_INTESTINE	Fedratinib →	+0.568	+2.652	.030	.045	3	1
LARGE_INTESTINE	XMD13-2 →	+0.475	+2.652	.027	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Leflunomide by GGNBP2 expression — LARGE_INTESTINE

Explore this box plot interactively →