GGH

Across TCGA patient cohorts, GGH protein abundance is significantly associated with the RNA expression of many other genes, with 12,254 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GGH-associated genes across cancer lineages are NCAPH, HJURP, and DLGAP5. Each is linked with GGH in more than 5 cancer types. Because this analysis shows association rather than direction, both GGH-to-partner and partner-to-GGH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GGH versus NCAPH in OV, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGH→partner) and Y-score (partner→GGH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NCAPH →	+0.829	+0.627	<.001	<.001	3	6
GBM	HJURP →	+1.321	+0.650	<.001	<.001	3	6
BRCA	DLGAP5 →	+1.055	+0.558	<.001	.003	3	6
OV	SGO1 →	+0.934	+1.144	<.001	<.001	3	6
GBM	KIF23 →	+1.198	+0.638	<.001	<.001	3	6
LSCC	CCDC150 →	+0.767	+0.389	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,254 associations by consensus.

GGH vs NCAPH — OV

Explore this scatter interactively →