GGH

Across TCGA cell cohorts, GGH RNA expression is significantly associated with the go_rna of many other GO terms, with 2,589 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible GGH-associated GO terms across cancer lineages are Mitotic spindle organization, Regulation of chromosome separation, and Negative regulation of metaphase/anaphase transition of cell cycle. Each is linked with GGH in more than 11 cancer types. Because this analysis shows association rather than direction, both GGH-to-partner and partner-to-GGH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle organization grouped by GGH-low versus GGH-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GGH→partner) and Y-score (partner→GGH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Mitotic spindle organization →	+0.118	+1.607	.004	.003	3	12
OESOPHAGUS	Regulation of chromosome separation →	+0.172	+1.339	.001	.001	3	11
OESOPHAGUS	Negative regulation of metaphase/anaphase transition of cell cycle →	+0.161	+1.500	.001	<.001	3	11
OESOPHAGUS	Microtubule cytoskeleton organization involved in mitosis →	+0.118	+1.416	.002	.009	3	11
OESOPHAGUS	Negative regulation of chromosome separation →	+0.161	+1.500	.001	<.001	3	11
OESOPHAGUS	Regulation of nuclear division →	+0.167	+1.869	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,589 associations by consensus.

Mitotic spindle organization by GGH expression — OESOPHAGUS

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