GGCX

Across TCGA patient cohorts, GGCX protein abundance is significantly associated with the RNA expression of many other genes, with 16,957 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GGCX-associated genes across cancer lineages are S100A11, CCM2L, and ZNF557. Each is linked with GGCX in more than 4 cancer types. Because this analysis shows association rather than direction, both GGCX-to-partner and partner-to-GGCX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GGCX versus S100A11 in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGCX→partner) and Y-score (partner→GGCX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	S100A11 →	+1.049	+0.449	<.001	<.001	3	4
CCRCC	CCM2L →	-0.879	-0.386	<.001	<.001	3	4
PDAC	ZNF557 →	-0.371	-0.550	.003	.001	3	4
UCEC	PLCL2 →	-0.815	-0.374	.002	.003	2	5
UCEC	ZNF443 →	-0.514	-0.386	.002	<.001	3	4
UCEC	ZNF823 →	-0.469	-0.388	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,957 associations by consensus.

GGCX vs S100A11 — GBM

Explore this scatter interactively →