GGCX

Across TCGA cell cohorts, GGCX RNA expression is significantly associated with the go_rna of many other GO terms, with 3,821 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GGCX-associated GO terms across cancer lineages are Negative regulation of testosterone biosynthetic process, Golgi vesicle transport, and Cytokinesis. Each is linked with GGCX in more than 13 cancer types. Because this analysis shows association rather than direction, both GGCX-to-partner and partner-to-GGCX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of testosterone biosynthetic process grouped by GGCX-low versus GGCX-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GGCX→partner) and Y-score (partner→GGCX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of testosterone biosynthetic process →	+0.318	+0.858	<.001	<.001	3	14
STOMACH	Golgi vesicle transport →	+0.066	+0.519	.001	.004	3	13
SKIN	Cytokinesis →	+0.059	+0.880	<.001	<.001	3	11
LARGE_INTESTINE	RISC complex assembly →	+0.098	+0.616	<.001	<.001	3	11
SKIN	Negative regulation of calcium ion export across plasma membrane →	+0.073	+0.878	<.001	<.001	3	11
LARGE_INTESTINE	Positive regulation of intracellular transport →	+0.050	+0.486	<.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,821 associations by consensus.

Negative regulation of testosterone biosynthetic process by GGCX expression — BONE

Explore this box plot interactively →