GGCT

Across TCGA patient cohorts, GGCT protein abundance is significantly associated with the RNA expression of many other genes, with 13,631 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GGCT-associated genes across cancer lineages are PEX1, MIOS, and ZNRF2. Each is linked with GGCT in more than 4 cancer types. Because this analysis shows association rather than direction, both GGCT-to-partner and partner-to-GGCT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GGCT versus PEX1 in LSCC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGCT→partner) and Y-score (partner→GGCT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PEX1 →	+0.753	+0.480	<.001	<.001	3	5
CCRCC	MIOS →	+0.509	+0.239	<.001	.001	3	5
BRCA	ZNRF2 →	+0.985	+0.610	<.001	<.001	3	5
BRCA	AVL9 →	+0.563	+0.703	<.001	<.001	3	4
BRCA	HIBADH →	+0.496	+0.365	<.001	<.001	3	4
LUAD	NOD1 →	+0.618	+0.393	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,631 associations by consensus.

GGCT vs PEX1 — LSCC

Explore this scatter interactively →