GGCT

Across TCGA cell cohorts, GGCT RNA expression is significantly associated with the go_rna of many other GO terms, with 4,973 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GGCT-associated GO terms across cancer lineages are DNA-templated DNA replication, Resolution of DNA recombination intermediates, and DNA replication. Each is linked with GGCT in more than 13 cancer types. Because this analysis shows association rather than direction, both GGCT-to-partner and partner-to-GGCT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication grouped by GGCT-low versus GGCT-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GGCT→partner) and Y-score (partner→GGCT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated DNA replication →	+0.135	+0.779	.009	.007	3	14
LUNG_NSCLC_LUSC	Resolution of DNA recombination intermediates →	+0.167	+0.745	.002	.001	3	14
UPPER_AERODIGESTIVE_TRACT	DNA replication →	+0.106	+1.256	<.001	<.001	3	13
BONE	DNA replication initiation →	+0.184	+0.927	.001	<.001	3	13
BLOOD_Myeloma	Interstrand cross-link repair →	+0.083	+1.252	.002	<.001	3	13
BLOOD_Myeloma	Positive regulation of DNA-directed DNA polymerase activity →	+0.172	+1.038	<.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,973 associations by consensus.

DNA-templated DNA replication by GGCT expression — BONE

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