GGA2

Across TCGA patient cohorts, GGA2 protein abundance is significantly associated with the RNA expression of many other genes, with 18,753 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GGA2-associated genes across cancer lineages are SLC15A3, APOC1, and CD74. Each is linked with GGA2 in more than 6 cancer types. Because this analysis shows association rather than direction, both GGA2-to-partner and partner-to-GGA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GGA2 versus SLC15A3 in GBM, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGA2→partner) and Y-score (partner→GGA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC15A3 →	+0.667	+0.355	<.001	<.001	3	7
UCEC	APOC1 →	+1.345	+0.161	<.001	.002	3	6
GBM	CD74 →	+1.121	+0.331	<.001	<.001	3	6
GBM	HLA-DMA →	+1.058	+0.397	<.001	<.001	3	6
GBM	HLA-DRA →	+1.222	+0.373	<.001	<.001	3	6
UCEC	HLA-DPA1 →	+1.333	+0.204	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,753 associations by consensus.

GGA2 vs SLC15A3 — GBM

Explore this scatter interactively →