GGA2

Across TCGA cell cohorts, GGA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,829 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GGA2-associated GO terms across cancer lineages are DNA strand elongation involved in DNA replication, Mitotic DNA integrity checkpoint signaling, and Response to hydroxyurea. Each is linked with GGA2 in more than 13 cancer types. Because this analysis shows association rather than direction, both GGA2-to-partner and partner-to-GGA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation involved in DNA replication grouped by GGA2-low versus GGA2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GGA2→partner) and Y-score (partner→GGA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA strand elongation involved in DNA replication →	+0.241	+1.264	<.001	<.001	3	14
BONE	Mitotic DNA integrity checkpoint signaling →	+0.129	+1.291	.001	.001	3	14
BONE	Response to hydroxyurea →	+0.165	+1.479	.001	<.001	3	13
BONE	Nuclear export →	+0.114	+1.040	<.001	.005	3	13
BONE	Centrosome duplication →	+0.140	+1.086	.001	.004	3	13
BONE	Regulation of DNA repair →	+0.102	+1.256	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,829 associations by consensus.

DNA strand elongation involved in DNA replication by GGA2 expression — BONE

Explore this box plot interactively →