GFY

Across TCGA pan-cancer cohorts, GFY RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of GFY’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where GFY RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GFY is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

LUAD, HNSC, and UCEC are the cancer types where GFY tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GFY RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.354	.002	7	view →
HNSC	Male	III,IV	+0.113	.001	7	view →
UCEC	All	All	+0.669	.001	6	view →
LUSC	All	II,III,IV	+0.316	<.001	5	view →
COAD	All	II,III,IV	+0.061	.018	4	view →
STAD	Male	All	+0.160	.003	2	view →
LIHC	All	All	+0.071	.007	2	view →
KIRC	All	All	−0.008	.034	2	view →
BRCA	All	All	+0.090	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

GFY–LUAD

Open the LUAD breakdown →