GFRA4

Across TCGA patient cohorts, GFRA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,441 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GFRA4-associated GO terms across cancer lineages are Mitochondrial membrane organization, Mitochondrial electron transport, NADH to ubiquinone, and Mesonephros development. Each is linked with GFRA4 in more than 9 cancer types. Because this analysis shows association rather than direction, both GFRA4-to-partner and partner-to-GFRA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial membrane organization grouped by GFRA4-low versus GFRA4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GFRA4→partner) and Y-score (partner→GFRA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial membrane organization →	+0.073	+0.134	<.001	<.001	2	10
STAD	Mitochondrial electron transport, NADH to ubiquinone →	+0.054	+0.076	<.001	<.001	3	8
STAD	Mesonephros development →	+0.032	+0.097	<.001	<.001	3	7
STAD	Cerebellar cortex morphogenesis →	+0.032	+0.076	<.001	<.001	3	7
STAD	Ribose phosphate biosynthetic process →	+0.070	+0.132	<.001	<.001	3	7
STAD	Regulation of actin nucleation →	+0.040	+0.078	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,441 associations by consensus.

Mitochondrial membrane organization by GFRA4 expression — STAD

Explore this box plot interactively →