GFRA4

Across TCGA cell cohorts, GFRA4 RNA expression is significantly associated with the mutation status of many other genes, with 259 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GFRA4-associated genes across cancer lineages are GGA3, ZNF142, and KRBA1. Each is linked with GFRA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both GFRA4-to-partner and partner-to-GFRA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GGA3 grouped by GFRA4-low versus GFRA4-high in SOFT_TISSUE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFRA4→partner) and Y-score (partner→GFRA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	GGA3 →	+3.584	+0.011	.004	.009	3	2
PANCREAS	ZNF142 →	+5.614	+0.016	.002	<.001	3	2
CNS	KRBA1 →	+5.754	+0.029	.002	<.001	3	2
LUNG_SCLC	KCNMA1 →	+4.087	+0.277	.002	<.001	3	2
LUNG_SCLC	MIB2 →	+4.087	+0.157	.002	.001	3	2
UPPER_AERODIGESTIVE_TRACT	TNXB →	+4.736	+0.013	.009	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 259 associations by consensus.

GGA3 by GFRA4 expression — SOFT_TISSUE

Explore this box plot interactively →