GFRA2

Across TCGA cell cohorts, GFRA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,304 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GFRA2-associated GO terms across cancer lineages are Lipoprotein transport, SRP-dependent cotranslational protein targeting to membrane, translocation, and Regulation of G0 to G1 transition. Each is linked with GFRA2 in more than 5 cancer types. Because this analysis shows association rather than direction, both GFRA2-to-partner and partner-to-GFRA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipoprotein transport grouped by GFRA2-low versus GFRA2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GFRA2→partner) and Y-score (partner→GFRA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Lipoprotein transport →	+0.171	+2.647	.007	.001	3	6
SKIN	SRP-dependent cotranslational protein targeting to membrane, translocation →	+0.113	+1.203	<.001	.007	3	6
SKIN	Regulation of G0 to G1 transition →	+0.050	+0.706	<.001	.005	3	6
BONE	Lipoprotein localization →	+0.164	+2.846	.007	<.001	3	5
LARGE_INTESTINE	Negative regulation of myoblast fusion →	+0.077	+0.030	<.001	.008	3	5
LARGE_INTESTINE	COPII-coated vesicle budding →	+0.059	+0.035	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,304 associations by consensus.

Lipoprotein transport by GFRA2 expression — BONE

Explore this box plot interactively →