GFPT2

Across TCGA cell cohorts, GFPT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,115 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GFPT2-associated GO terms across cancer lineages are Peptidyl-lysine oxidation, Positive regulation of focal adhesion assembly, and Regulation of ATP-dependent activity. Each is linked with GFPT2 in more than 12 cancer types. Because this analysis shows association rather than direction, both GFPT2-to-partner and partner-to-GFPT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine oxidation grouped by GFPT2-low versus GFPT2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GFPT2→partner) and Y-score (partner→GFPT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Peptidyl-lysine oxidation →	+1.298	+3.097	<.001	<.001	3	13
BREAST	Positive regulation of focal adhesion assembly →	+0.192	+2.715	<.001	<.001	3	13
STOMACH	Regulation of ATP-dependent activity →	+0.126	+2.324	<.001	.001	3	12
BONE	Regulation of cell-substrate junction assembly →	+0.153	+2.741	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Elastin metabolic process →	+0.301	+2.761	.001	<.001	3	12
BONE	Regulation of focal adhesion assembly →	+0.153	+2.741	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,115 associations by consensus.

Peptidyl-lysine oxidation by GFPT2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →