GFPT2

Across TCGA cell cohorts, GFPT2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GFPT2-associated genes across cancer lineages are NAT8B, IFNA7, and ACER1. Each is linked with GFPT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GFPT2-to-partner and partner-to-GFPT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NAT8B grouped by GFPT2-low versus GFPT2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFPT2→partner) and Y-score (partner→GFPT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	NAT8B →	+0.090	+4.350	<.001	.005	3	1
BLOOD_Lymphoma	IFNA7 →	+0.026	+4.643	<.001	.005	3	1
LARGE_INTESTINE	ACER1 →	+0.117	+3.145	<.001	.004	3	1
LARGE_INTESTINE	ACKR1 →	+0.046	+3.617	<.001	.004	3	1
BLOOD_Leukemia	OR1G1 →	+0.080	+4.705	<.001	.003	3	1
BLOOD_Leukemia	TSSK1B →	+0.019	+4.874	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

NAT8B by GFPT2 expression — BLOOD_Lymphoma

Explore this box plot interactively →