GFPT1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GFPT1 mutation is significantly associated with the RNA expression of many other genes, with 3,527 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GFPT1-associated genes across cancer lineages are VN1R64P, RNA5SP411, and RNA5SP412. Each is linked with GFPT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GFPT1-to-partner and partner-to-GFPT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFPT1→partner) and Y-score (partner→GFPT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCVN1R64P →+0.024+4.516<.001.00432
UCECRNA5SP411 →+1.084+1.531<.001.00532
UCECRNA5SP412 →+0.743+1.896<.001.00132
BRCAS100A11P8 →+0.109+8.471<.001.00532
SKCMRNU1-74P →+0.344+4.877<.001<.00132
SKCMMIR892A →+0.428+4.947<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,527 associations by consensus.

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