GFOD2

Across TCGA patient cohorts, GFOD2 mutation is significantly associated with the RNA expression of many other genes, with 822 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GFOD2-associated genes across cancer lineages are LINC00489, SPEM2, and MRPS21P5. Each is linked with GFOD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GFOD2-to-partner and partner-to-GFOD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00489 grouped by GFOD2-low versus GFOD2-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFOD2→partner) and Y-score (partner→GFOD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	LINC00489 →	+0.216	+7.276	<.001	<.001	3	2
LUAD	SPEM2 →	+0.148	+3.658	<.001	.005	3	2
LUSC	MRPS21P5 →	+0.436	+4.365	<.001	.007	3	2
SKCM	RNU6-1208P →	+0.395	+5.037	<.001	.009	3	2
LUSC	BUD31P1 →	+0.163	+4.792	.006	.006	3	2
UCEC	TRAJ22 →	+0.548	+1.939	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 822 associations by consensus.

LINC00489 by GFOD2 expression — READ

Explore this box plot interactively →