GFOD2

Across TCGA cell cohorts, GFOD2 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible GFOD2-associated genes across cancer lineages are CCDC42, CCDC185, and SUPT20HL1. Each is linked with GFOD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GFOD2-to-partner and partner-to-GFOD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC42 grouped by GFOD2-low versus GFOD2-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFOD2→partner) and Y-score (partner→GFOD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	CCDC42 →	+0.026	+3.432	<.001	.008	3	1
STOMACH	CCDC185 →	+0.110	+3.584	<.001	.009	3	1
STOMACH	SUPT20HL1 →	+0.005	+3.794	<.001	.003	3	1
STOMACH	CTXND2 →	+0.028	+3.432	<.001	.008	3	1
STOMACH	ITGA8 →	+0.051	+4.442	<.001	.002	3	1
LARGE_INTESTINE	PTH →	+0.063	+4.684	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

CCDC42 by GFOD2 expression — STOMACH

Explore this box plot interactively →