GFOD1

Across TCGA patient cohorts, GFOD1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,002 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GFOD1-associated genes across cancer lineages are RAPGEF3, FAM107A, and CNFN. Each is linked with GFOD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GFOD1-to-partner and partner-to-GFOD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GFOD1 versus RAPGEF3 in CCRCC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFOD1→partner) and Y-score (partner→GFOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RAPGEF3 →	+1.050	+0.441	<.001	<.001	3	5
CCRCC	FAM107A →	+1.399	+0.528	.006	.002	3	4
HNSC	CNFN →	+1.591	+0.425	.005	<.001	3	3
LSCC	CDKN1A →	+0.694	+0.244	<.001	<.001	3	3
CCRCC	HIGD1B →	+1.575	+0.641	<.001	<.001	3	3
HNSC	THSD1 →	+0.885	+0.504	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,002 associations by consensus.

GFOD1 vs RAPGEF3 — CCRCC

Explore this scatter interactively →