GFOD1

Across TCGA patient cohorts, GFOD1 mutation is significantly associated with the RNA expression of many other genes, with 1,692 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GFOD1-associated genes across cancer lineages are MIR7702, CPLX3, and RNA5SP478. Each is linked with GFOD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GFOD1-to-partner and partner-to-GFOD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7702 grouped by GFOD1-low versus GFOD1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFOD1→partner) and Y-score (partner→GFOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR7702 →	+0.116	+3.784	<.001	.009	3	3
CESC	CPLX3 →	+0.014	+4.342	<.001	.007	3	2
BLCA	RNA5SP478 →	+0.185	+4.314	.005	.009	3	2
UCEC	CMC1 →	+0.271	+2.108	.007	.002	3	2
UCEC	FANCA →	+0.561	+1.928	<.001	.008	3	2
CESC	MIR3619 →	+1.066	+3.893	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,692 associations by consensus.

MIR7702 by GFOD1 expression — SKCM

Explore this box plot interactively →