GFOD1

Across TCGA cell cohorts, GFOD1 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GFOD1-associated genes across cancer lineages are C6orf118, NDUFAF1, and RPL7L1. Each is linked with GFOD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GFOD1-to-partner and partner-to-GFOD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C6orf118 grouped by GFOD1-low versus GFOD1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFOD1→partner) and Y-score (partner→GFOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.118	+2.793	<.001	.002	3	1
LARGE_INTESTINE	NDUFAF1 →	+0.718	+3.064	<.001	.009	3	1
LARGE_INTESTINE	RPL7L1 →	+0.677	+3.169	.001	.005	3	1
LARGE_INTESTINE	NTMT1 →	+0.554	+3.067	.002	.009	3	1
LARGE_INTESTINE	CDC20B →	+0.062	+3.999	.001	<.001	3	1
LARGE_INTESTINE	NKX3-1 →	+1.370	+3.082	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

C6orf118 by GFOD1 expression — LARGE_INTESTINE

Explore this box plot interactively →