GFM2

Across TCGA cell cohorts, GFM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,906 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GFM2-associated GO terms across cancer lineages are Translational termination, 7-methylguanosine RNA capping, and Regulation of centriole replication. Each is linked with GFM2 in more than 12 cancer types. Because this analysis shows association rather than direction, both GFM2-to-partner and partner-to-GFM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Translational termination grouped by GFM2-low versus GFM2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GFM2→partner) and Y-score (partner→GFM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Translational termination →	+0.118	+0.662	<.001	<.001	3	13
SOFT_TISSUE	7-methylguanosine RNA capping →	+0.077	+0.464	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of centriole replication →	+0.078	+0.719	.006	.002	3	10
SOFT_TISSUE	7-methylguanosine mRNA capping →	+0.077	+0.464	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Nucleotide-excision repair →	+0.089	+0.979	<.001	<.001	3	10
SKIN	Proteasome regulatory particle assembly →	+0.092	+0.576	.003	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,906 associations by consensus.

Translational termination by GFM2 expression — URINARY_TRACT

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