GFM1

Across TCGA patient cohorts, GFM1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,158 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GFM1-associated genes across cancer lineages are LHFPL6, GIMAP6, and VSTM4. Each is linked with GFM1 in more than 7 cancer types. Because this analysis shows association rather than direction, both GFM1-to-partner and partner-to-GFM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GFM1 versus LHFPL6 in COAD, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFM1→partner) and Y-score (partner→GFM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LHFPL6 →	-0.712	-0.404	.001	<.001	3	8
LSCC	GIMAP6 →	-0.676	-0.323	<.001	<.001	3	7
BRCA	VSTM4 →	-0.650	-0.244	.001	.003	3	7
BRCA	ADCY4 →	-0.836	-0.343	<.001	<.001	3	6
BRCA	ADAMTS10 →	-0.627	-0.213	<.001	.001	3	6
UCEC	PTH1R →	-0.762	-0.335	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,158 associations by consensus.

GFM1 vs LHFPL6 — COAD

Explore this scatter interactively →