GFM1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GFM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,026 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GFM1-associated GO terms across cancer lineages are Ribosomal subunit export from nucleus, Ribosome localization, and Replication fork processing. Each is linked with GFM1 in more than 14 cancer types. Because this analysis shows association rather than direction, both GFM1-to-partner and partner-to-GFM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal subunit export from nucleus grouped by GFM1-low versus GFM1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GFM1→partner) and Y-score (partner→GFM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCRibosomal subunit export from nucleus →+0.118+0.629<.001<.001315
LUNG_SCLCRibosome localization →+0.118+0.629<.001<.001315
UPPER_AERODIGESTIVE_TRACTReplication fork processing →+0.112+1.048<.001<.001314
PANCREAStRNA wobble guanine modification →+0.111+0.938<.001<.001313
LIVERMitochondrial gene expression →+0.083+0.971.002<.001213
UPPER_AERODIGESTIVE_TRACTDNA-templated DNA replication maintenance of fidelity →+0.115+1.135<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,026 associations by consensus.

Ribosomal subunit export from nucleus by GFM1 expression — LUNG_SCLC

Box plot of Ribosomal subunit export from nucleus in GFM1-low vs GFM1-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration