GFM1

Across TCGA cell cohorts, GFM1 mutation is significantly associated with the RNA expression of many other genes, with 363 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GFM1-associated genes across cancer lineages are OR51T1, GSG1L2, and CBY1. Each is linked with GFM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GFM1-to-partner and partner-to-GFM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51T1 grouped by GFM1-low versus GFM1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFM1→partner) and Y-score (partner→GFM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR51T1 →	+0.052	+3.922	<.001	.002	3	1
BLOOD_Leukemia	GSG1L2 →	+0.028	+3.969	<.001	.009	3	1
LARGE_INTESTINE	CBY1 →	+0.677	+3.299	<.001	.004	3	1
LARGE_INTESTINE	EIF3D →	+0.467	+3.212	.003	.006	3	1
LARGE_INTESTINE	SH3GL2 →	+1.240	+3.252	<.001	.009	3	1
LARGE_INTESTINE	TRIM37 →	+0.693	+3.212	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 363 associations by consensus.

OR51T1 by GFM1 expression — BLOOD_Leukemia

Explore this box plot interactively →