GFI1B

Across TCGA patient cohorts, GFI1B mutation is significantly associated with the RNA expression of many other genes, with 1,248 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GFI1B-associated genes across cancer lineages are RNU6-280P, EIF3JP1, and BZW1-AS1. Each is linked with GFI1B in more than 1 cancer types. Because this analysis shows association rather than direction, both GFI1B-to-partner and partner-to-GFI1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-280P grouped by GFI1B-low versus GFI1B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFI1B→partner) and Y-score (partner→GFI1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-280P →	+0.277	+5.488	<.001	.001	3	2
UCEC	EIF3JP1 →	+0.218	+2.005	<.001	.004	3	2
UCEC	BZW1-AS1 →	+0.243	+4.628	<.001	<.001	3	2
UCEC	VDAC3P1 →	+0.335	+2.233	<.001	.005	3	1
UCEC	CCL5 →	+0.939	+2.191	.005	.002	3	1
UCEC	ARF4P1 →	+0.372	+2.543	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,248 associations by consensus.

RNU6-280P by GFI1B expression — SKCM

Explore this box plot interactively →