GFI1B

Across TCGA cell cohorts, GFI1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,219 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GFI1B-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Termination of RNA polymerase II transcription, and Establishment of protein localization to organelle. Each is linked with GFI1B in more than 7 cancer types. Because this analysis shows association rather than direction, both GFI1B-to-partner and partner-to-GFI1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by GFI1B-low versus GFI1B-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GFI1B→partner) and Y-score (partner→GFI1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.066	+0.079	<.001	.002	3	8
OVARY	Termination of RNA polymerase II transcription →	+0.097	+0.107	<.001	.002	3	7
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to organelle →	+0.039	+0.053	.001	.003	3	7
CNS	Negative regulation of myoblast fusion →	+0.053	+0.059	<.001	.002	3	6
BONE	Positive regulation of protein-containing complex assembly →	+0.036	+0.085	.001	.001	3	6
OVARY	Regulation of myoblast fusion →	+0.074	+0.105	.002	.002	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,219 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by GFI1B expression — CNS

Explore this box plot interactively →